![]() ![]() 7 Moreover, patients with mental illness exhibit unique risk factors for DM, such as the use of antipsychotic medications. 6 8Īge, obesity, hypertension, hyperlipidemia, and sedentary lifestyle are well-documented risk factors for DM, and many of these risk factors are more common in people with psychotic disorders than in the general population, which is partly explained by adverse health behaviors. 7 Patients with serious mental illness (SMI), such as schizophrenia, demonstrate 1.5–2-fold prevalence of T2DM and have poorer long-term outcomes, including increased tendency for relapse of mental illness and increased mortality secondary to an increased risk of cardiovascular disease. 6 Furthermore, the prevalence of DM is generally reported to be higher in people with psychotic disorders than in those with other types of mental illnesses. ![]() 2 The prevalence of DM is often reported to be higher in psychiatric inpatients than in the general population. 4 5ĭM imposes a substantial physical and psychological burden on patients, resulting in a decline in health status and quality of life. 4 In China, the prevalence of DM has grown rapidly in the past decade, increasing from 2.6% in 2002 to 10.9% in 2013. 3 Rapid socioeconomic development and considerable changes in dietary patterns, behavior, and lifestyle have contributed to the rapidly increasing risk of T2DM. 2 According to an estimate by the International Diabetes Federation, 425 million adults aged 20–79 years worldwide had T2DM in 2017, and the areas that were particularly affected by DM were China and India. 1 Type 2 diabetes mellitus (T2DM), resulting from impaired insulin secretion, insulin resistance, or a combination of both conditions, is far more common than other types of DM T2DM accounts for more than 90% of all DM cases. Age-specific prevalence of T2DM under a stratification of schizophrenia or other psychiatric disorders was calculated in the subgroup analysis.ĭiabetes mellitus (DM) is a global public health crisis that threatens the economies of all nations, particularly those of developing countries. ![]() Univariate and multivariate logistic regression analyses were performed to obtain crude ORs and adjusted ORs (aORs) on the risk of T2DM in patients with different demographic characteristics, schizophrenia, antipsychotic medication use, and different comorbidities. The overall prevalence of T2DM in adult psychiatric inpatients was calculated, and the annual prevalence of T2DM was calculated and adjusted to the overall participant population. Schizophrenia, T2DM, and comorbidities were defined according to the International Classification of Diseases, 10th revision codes of discharge diagnosis. Data on demographic characteristics and antipsychotic medication use were obtained from electronic health records. Research design and methods We did a longitudinal observational study using data from the Beijing Municipal Commission of Health and Family Planning Information Center, including 157 570 adult psychiatric inpatients in 19 specialized psychiatric hospitals from 2005 to 2018 in Beijing. ![]()
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